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Food based phytochemical luteolin their derivatives, sources and medicinal benefits

Muhammad Faisal Manzoor1*, Nazir Ahmad1, Ahsan Manzoor2, Ayesha K
Published 28-06-2017

DOI

http://dx.doi.org/10.22573/spg.ijals.017.s12200084

AUTHOR AFFILIATION

1Institute of Home and Food Sciences, Faculty of Sciences and Technology, Government College University Faisalabad, Pakistan. 2Department of Chemistry, Faculty of Sciences and Technology, Government College University Faisalabad, Pakistan.

ARTICLE HISTORY

Received: June 2017 / Accepted: June 2017/ Published: June 2017

HOW TO CITE THIS ARTICLE

Manzoor, M. F., Ahmad, N., Manzoor, A., & Kalsoom, A. (2017). Food based phytochemical luteolin their derivatives, sources and medicinal benefits. Int. J. Agr. Life. Sci, 3(2), 195-207. doi: 10.22573/spg.ijals.017.s12200084.

COPYRIGHT

© 2017 Skyfox Publishing Group. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

COMPETING INTERESTS

The authors have declared that no competing interests exist.

ABSTRACT

Luteolin is a type of flavonoid and a 38, 48, 5, 7-tetra hydroxyl flavone with a yellow crystalline appearance. Luteolin is widely present in different plant families such as, Lamiacea, Arecaceae, Brassicaceae, Campanulaceae, Asteraceae, Resedaceae and Scrophulariaceae. Luteolin mostly found in edible plants and most important food based phytochemical. Dietary sources of luteolin such as, celery, peppers, carrots, peppermint, olive oil, thyme, oregano and rosemary, etc. On the base of luteolin content among other sources oregano is the better source with 1028.75mg/100g contents. Flavonoids are important component of plants, and widely used in traditional medicine to cure the different type of diseases. Luteolin has different health benefits such as, anti-inflammatory, sun protectant, anti-oxidant, improve heart function, neurological impairments, anti-cancer and many more. Luteolin has many possible mechanisms involved in different biological activities such as, stabilization of p53, modulation of ROS levels, and reduction of NF- kappaB, reduction of AP-1 activity and inhibition of PI3K.